The state of Wisconsin currently has 15 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Milwaukee, Madison, Green Bay and Marshfield.
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
Recruiting
The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to requests for opioid refills. Additionally, the investigators believe there will be no significant difference in postoperative readmission for pain quality of life at 30 days in either group.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Postoperative Pain, Inguinal Hernia
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Interventional Pain Specialists of Wisconsin, Rice Lake, Wisconsin
Conditions: Chronic Pain
Osteopathic Manual Treatment for Hemiplegic Shoulder Pain and Upper Extremity Function in Stroke Patients
Recruiting
This study assesses the feasibility and safety of performing osteopathic manual treatment (OMT) for hemiplegic shoulder pain in stroke patients. This study's participants will be adults with a first-time stroke diagnosis in the past 5 years and shoulder pain on the same side affected by stroke. Eligible participants will be placed on study for approximately 6 weeks and given either OMT or a sham treatment each week.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2024
Locations: UW Health University Ave Rehabilitation Clinic, Middleton, Wisconsin
Conditions: Hemiplegic Shoulder Pain, Osteopathic Manipulative Treatment
RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Advanced Pain Management Appleton, Greenfield, Wisconsin
Conditions: Pain
EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA
Recruiting
The purpose of this study is to investigate the safety and efficacy of the current hard gelatin capsule formulation of NRD135S.E1 80 mg once daily in the treatment of PDPN when administered for 13 weeks.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Painful Diabetic Neuropathy
EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy
Recruiting
This is a Platform Protocol to perform Phase II clinical trials in The Early Phase Pain Investigation Clinical Network (EPPIC-Net), under The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, related to the treatment of Painful Diabetic Peripheral Neuropathy (PDPN) in a platform setting to test multiple assets under a single protocol.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Painful Diabetic Neuropathy
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
All
Ages:
Between 0 years and 20 years
Trial Updated:
03/29/2024
Locations: University of Wisconsin, Madison, Wisconsin +2 locations
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction
Recruiting
STACI is a prospective, multicenter, study of SIJ fusion using the iFuse TORQ implant system.
Gender:
All
Ages:
21 years and above
Trial Updated:
03/05/2024
Locations: Pro Spine and Pain, Milwaukee, Wisconsin
Conditions: Sacroiliac Joint Dysfunction, Sacroiliac; Fusion, Sacroiliac Disorder, Sacroiliac Joint Pain
Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain
Recruiting
This Registry study will prospectively evaluate the differences in treatment outcomes in terms of pain intensity, pain interference, concomitant medication use, health-related quality of life, opioid adverse effects, and healthcare utilization between targeted drug delivery and conservative medication management only groups.
Gender:
All
Ages:
21 years and above
Trial Updated:
01/15/2024
Locations: Advocate Aurora Health, Oshkosh, Wisconsin
Conditions: Cancer Pain, Chronic Pain, Cancer Associated Pain, Neuropathic Pain
Ketamine for Pain Control After Severe Traumatic Injury
Recruiting
This study evaluates if the early utilization of ketamine infusion therapy among acutely injured adult trauma hospital inpatients with an ISS >15 will decrease the amount of opioid pain medication used as compared with placebo group. Ketamine infusion therapy initiated within 12 hours of hospital arrival will lead to decreased total opiate consumption (standardized to oral morphine equivalent units) in the first 24 and 48 hours compared to controls.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
11/08/2023
Locations: Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Hospital Inpatient Trauma Injury, Pain Management
BurstDR Stimulation for Painful Diabetic Neuropathy
Recruiting
This study aims to demonstrate treatment outcomes of Painful Diabetic Neuropathy (PDN) patients treated with BurstDRTM Spinal Cord Dorsal Column Stimulator (SCS) along with conservative medical management per standard of care.
Gender:
All
Ages:
22 years and above
Trial Updated:
08/09/2023
Locations: Aurora Health Oshkosh, Oshkosh, Wisconsin
Conditions: Painful Diabetic Neuropathy
Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery
Recruiting
The purpose of this study is to determine if ultrasound-guided bilateral pectointercostal fascial plane blocks with bilateral rectus sheath blocks block decrease pain scores, decrease opioid consumption, improve respiratory function, and improve quality of recovery in patients recovering from elective cardiac surgery involving primary median sternotomy and mediastinal chest tubes in comparison to pectointercostal fascial plane blocks alone.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/07/2023
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Coronary Artery Disease, Postoperative Pain, Respiratory Failure